Cannabis vs. Chronic Itch: Surprising New Research

Bottom Line Takeaways:

• Cannabis as a potential treatment for itchiness: A recent study explores how cannabinoids in a topical cream may help people with chronic kidney disease reduce severe itching (pruritus).

• Study details: The study included 60 patients undergoing hemodialysis, with half receiving the cannabis cream and the other half receiving a placebo.

• Significant improvement: After four weeks, the group using the cannabis cream saw a marked reduction in their itchiness, backed by standardized questionnaires measuring the severity and impact on daily life.

• How cannabis works on itch: Cannabinoids interact with the body’s endocannabinoid system, which regulates various functions like pain and inflammation. These compounds may reduce inflammation and disrupt the signals between the skin and brain that cause the itchy sensation.

• It’s not just about scratching less: Patients reported an overall improvement in their quality of life, making this more than just a surface-level treatment.

• Study limitations: This was a small study with a short follow-up period. More research is needed to confirm long-term effects, optimal dosages, and whether the results apply to other types of chronic itch.

1. For more about topicals and recipes for DIYing them yourself: CED Clinic Topicals

2. For Do-It-Yourself Products, Edibles, and Topicals, Chapter 4 of The Doctor-Approved Cannabis Handbook

3. The Audiobook Version